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| BIOINFORMATICS |
(BINF) |
| 3307 Mathematical Modeling in Biology
|
3 hours |
| An introduction to ordinary differential equations
and their applications to biology. Topics include: first order
differential equations, first order systems, linear systems,
non-linear systems, forcing and resonance, numerical methods,
and dynamical systems, as time permits. Biological modeling
and examples drawn from research articles in biology will
be incorporated throughout the course. Same as MATH 3307.
Prerequisite: MATH 2314, BIOL 1307/1107 and 1308/1108. SPRING |
| 3322 Biostatistics |
3 hours |
| An introduction to statistical methods and their
application to biology. Topics include: multiple regression,
2-way ANOVA, non-parametric tests, experimental design, Markov
chains and Hidden Markov models. Biological examples will
be emphasized throughout. Same as MATH 3322. Prerequisite:
MATH 3320, BIOL 1307/1107 and 1308/1108. SPRING |
| 3338 Numerical & Scientific Methods
|
3 hours |
| A survey of standard techniques used to solve
numerical and other science-based problems. Topics include
roots of equations, systems of linear equations, curve fitting,
numerical integration and differentiation, error analysis,
number representation, and data visualization. Problems will
be solved using programs written in appropriate languages
and operating systems. Same as COSC and MATH 3338. Pre-requisites:
MATH 2314 and COSC 2323. SPRING, odd-numbered years |
| 4310 Bioinformatics |
3 hours |
| A survey course of the main problems and methods
in Bioinformatics. Among the topics that may be included are:
protein & nucleic acid sequence alignments (sequence databases,
the use of the algorithm BLAST, multiple sequence alignments),
large biological database analysis (genome sequencing and
genome assembly, gene finding algorithms, DNA microarrays
and large gene expression data sets, clustering algorithms),
protein structure analysis (protein structure comparison,
protein structure databases, fold recognition, 3D-1D profiles,
threading, comparative structure modeling), phylogeny (evolutionary
trees), biological networks (pathway analysis, properties
of biological graphs), algorithms in computer sciences inspired
by biology (genetic algorithms, DNA computing, neural networks,
and path optimization). Pre-requisite: COSC 2327, MATH 3302,
and BIOL 3334. FALL. |
| 4147 Research Methods |
1 hour |
| An introduction to research methods in bioinformatics
and the research of relevant literature. Course activities
include an overview of research methodology in bioinformatics,
computer database searches and the preparation of research
proposals. Each student will identify a research problem,
and write a complete paper or research proposal in consultation
with a faculty member. Course emphasis is placed on written
and oral presentation of the student’s research proposal.
Co- or pre-requisite: BINF 4310, junior or senior standing.
FALL. |
| 4148 Undergraduate Research |
1 hour |
| With faculty guidance, a student selects a research
question and conducts an independent investigation in order
to examine the question. Research projects are divided into
modules that can be reasonably completed in one semester.
Students are encouraged and facilitated in presentation of
their findings at a scientific meeting and publication in
a scholarly journal. Prerequisite: BINF 4310 and the consent
of the instructor. SPRING, FALL, SUMMER. |
| 4149 Senior Seminar |
1 hour |
| A seminar presentation based on the student’s
own undergraduate research results. The course also requires
a written presentation of the seminar according to scholarly
standards. Students will be required to take one of the Major
Field Achievement Tests as part of this course. Prerequisite:
BINF 4147, BINF 4148, and the consent of the instructor, and
senior standing. SPRING. |
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