Charles Hauser, Ph.D. is a bioinformatician with a background in plant genetics, genomics and molecular biology. His current research interests focus on (1) soil metagenomics – identifying plant microbe interactions, and (2) examining the potential toxicity of nanoparticles in environmental systems
Dr. Hauser received his undergraduate training in botany and chemistry from the University of Texas, Austin. While there he carried out a plant survey for land overlooking Redbud Island in Austin. Upon graduation, he worked with a group at Shell Research studying the formulation of solid resins used in a diverse array of products from sailboat hulls to carbon-fiber bicycles. Dr. Hauser returned academics, receiving his to earn his Ph.D. in Biochemistry and Biophysics working with Dr. H. Gray at the University of Houston. where his research focused on the enzymology of the nuclease BAL31, a dual-functional endo- and exo-nuclease, and the cloning of the gene. Dr. Hauser went to Duke University working with Drs. N.W. Gillham and J.E. Boynton where his post-doctoral research focused on characterization of chloroplast post-transcriptional regulation mechanisms in the unicellular green alga, Chlamydomonas reinhardtii. Dr. Hauser extended his stay at Duke, where as a research scientist he was involved with building the first set of gene models for the Chlamydomonas genome projec, and later with annotation of the draft genomic sequence generated by DOE-JGI in collaboration with Dr. Arthur Grossman at Stanford. Dr. Hauser came to St. Edward's in 2004 to establish the Bioinformatics Program.
Associate Professor, 2008 - present
Assistant Professor, 2004 - 2008
Postdoctoral Associate: Duke University,1989 - 1995
Research Associate Duke University, 1995 - 2000
Research Scientist Duke University, 2000 - 2004
Research Scientist, Duke University
Post Doctoral, Duke University
PhD. Biochemistry and Biophysics at University of Houston
Botany, University of Texas, Austin
Achievement & Involvement
Honors and Awards
2016 St. Edward’s School of Natural Sciences Distinguished Research Award, 2015-16
1990 NIH Postdoctoral Fellowship. Department of Botany, Duke University, Durham, NC.
1989 Hargitt Fellowship. Department of Zoology, Duke University, Durham, NC.
Genomics Education Partnership, Washington University St Louis, St. Louis MO July 23-26, 2016
Galaxy "G-OnRamp" Workshop, Washington University St Louis, St. Louis MO July 27-28, 2016
McNair Symposium July 9, 2015
Genomics Education Conference, St. Louis MO, July 25-29, 2015
HHMI Science Education Alliance 6th Annual Symposium Janelia Research Campus June 13-15, 2014
Network for Integrating Bioinformatics into Life Sciences Education (NIBLSE) Omaha NE, April 17-18, 2014
Undergraduate Bioinformatics Education Conference St. Vincent College, PA 2012, 20123
<p>2016 NSF, IUSE, “Integrating Bioinformatics into the Life Sciences—Phase 3” Mark Pauley (U. Nebraska, Omaha), Vince Buonaccorsi (Juniata College), Anya Goodman (California Polytechnic State University), Anne Rosenwald (Georgetown University) and Bill Tapprich (University of Nebraska at Omaha) Co-PIs. Charles Hauser (Advisory Committee ) </p>
<p>2015 USDA, The Agricultural-STEM Pipeline: Progressive Experiential Learning Linking Three HSI Academic Tiers (Ag-STEM), 3 year ($275,000), Drs. O’Leary (PI), Quinn, Hauser, Deaton (co-PIs)</p>
<p>2015 NIH, “A Genome Browser On Ramp to Engage Biologists with Big Data”, Dr. Sarah Elgin, Washington University St. Louis (PI), Hauser (collaborator). Funded</p>
<p>2014 National Science Foundation’s S-STEM, “Rewarding Achievement in Mathematics and Sciences (RAMS) Scholarships.” DUE-1356496. $607,830 (co-PI)</p>
Previously Awarded Grants
<p>2012 WM Keck Foundation, Undergraduate Education Phase I Proposal, “The Wild Basin Wilderness Preserve Digital Database”, $200,000 (co-PI)</p>
<p>2010 NSF-STEP #0969153, Community for Achievement in Science, Academics, and Research (co-PI)</p>
<p>2014 Lola Wright Foundation, “Strengthening the Bioinformatics Program for Enhanced Student Success” ”. $9000 (PI)</p>
<p>2007 W. M. Keck Foundation, Collaborative Research – A Novel Experiential Pedagogy (co-PI)</p>
Publications & Articles
Callejon, A.C., Douglas, D., Fox, D.J., Harper, M., Hyde, N.V., Lerma, J.F., Parsons, S.C., Suarez, C., Walsh, M.A., Kart, M., Hauser, C.R., Hughes, L.E., Bradley, K.W., Asai, D.J., Bowman, C.A., Russell, D.A., Pope, W.H., Jacobs-Sera, D., Hendrix, R.W. and Hatfull, G.F., Mycobacterium phage LadyBird, complete genome. GenBank Accession Number KT588442
Leung, W, Hauser,CR,...Elgin, SCR (2015) "The Drosophila Muller F elements maintain a distinct set of genomic properties over 40 million years of evolution." G3 March 4, 2015, doi: 10.1534/g3.114.015966. [Total 940 student co-authors, 74 faculty co-authors.]
Shaffer CD, ..., Hauser C, Mardis ER, Buhler J, Leung W, Lopatt D, Elgin SCR.2014. A course-based research experience: How benefits change with increased investment in instructional time. Cell Biology Education - Life Science Education 13: 111-130
Lopatto,D., Hauser, C, J... Elgin, S.C.R 2014. A Central Support System Can Facilitate Implementation and Sustainability of a Classroom-Based Undergraduate Research Experience (CURE) in Genomics. Cell Biology Education - Life Science Education.13(4):711-23.
Shaffer, CD, … C Hauser, ER Mardis, J Buhler, W Leung, DE Lopatto, SCR Elgin (2014) A course-based research experience: How benefits change with increased investment in instructional time. CBE—Life Sciences Education 13, 111–130, Spring 2014
Simon, D.F., Domingos, R.F., Hauser, C. Hutchins,C.M., Zerges, W. and Wilkinson.K.J. RNA-Seq analysis of the effects of metal nanoparticle exposure on the transcriptome of Chlamydomonas reinhardtii. (2013) Applied and Environmental Microbiology 9(16):4774-85
Domingos, Rute, Simon, Dana, Hauser, Charles, Wilkinson, Kevin (2011) Bioaccumulation and effects of CdTe/CdS quantum dots on Chlamydomonas reinhardtii – nanoparticle or the free ion? Environ. Sci. Technol., 2011, 45 (18), 7664–7669
Christopher D. Shaffer, Charles Hauser, ... Wilson Leung, Jeremy Buhler, Elaine R. Mardis, David Lopatto, and Sarah C.R. Elgin The Genomics Education Partnership: Successful Integration of Research into Laboratory Classes at a Diverse Group of Undergraduate Institutions CBE Life Sci Educ 2010: 55–69
Healy, Eamonn F, Johnson, Skylar, Hauser, Charles R, King, Peter J (2009) Tyrosine Kinase Inhibition: Ligand binding and conformational change in c-Kit and c-Abl FEBS Lett.583, 2899-2906
D. Lopatto, C. Alvarez, D. Barnard, C. Chandrasekaran, H.-M. Chung, C. Du, T. Eckdahl, A. L. Goodman, C. Hauser, C. J. Jones, O. R. Kopp, G. A Kuleck, G. McNeil, R. Morris, J. L. Myka, A. Nagengast, P. J. Overvoorde, J. L. Poet, K. Reed, G. Regisford, D. Revie, A. Rosenwald, K. Saville, M. Shaw, G. R. Skuse, C. Smith, M. Smith, M. Spratt, J. Stamm, J. S. Thompson, B. A. Wilson, C. Witkowski, J. Youngblom, W. Leung, C. D. Shaffer, J. Buhler, E. Mardis, S. C. R. Elgin (2008) Undergraduate Research: Genomic Education Partnership, Science 322(5902), 684
William Zerges and Charles Hauser (2008) Protein Synthesis in the Chloroplast In: The Chlamydomonas Sourcebook Volume II. (E. Harris, D. Stern, G. Witman Eds.) pp 967- 1028 Academic Press
1. Sabeeha Merchant et al. (2007) The Chlamydomonas genome reveals evolutionary insights into key animal and plant functions. Science 2007 318:245-251
Monica Jain, Jeff Shrager, Elizabeth Harris, Arthur Grossman, Charles Hauser and Olivier Vallon, (2007) EST assembly supported by a draft genome sequence: an analysis of the Chlamydomonas reinhardtii transcriptome. Nucl. Acids Res. 2007 35: 2074-2083
Arthur R. Grossman, Elizabeth E. Harris, Charles Hauser, Paul A. Lefebvre, Diego Martinez, Dan Rokhsar, Jeffrey Shrager, Carolyn Silflow, David Stern, Olivier Vallon, Zhaoduo Zhang (2003) Chlamydomonas reinhardtii at the crossroads of genomics. Eukaryotic Cell, 2(6),1137-1150
Charles Hauser (2014), “Bioinformatics at an Undergraduate Institution”. Network for Integrating Bioinformatics into Life Sciences Education. Omaha, NB April 16-18, 2014.
Charles Hauser (2013), RNASeq: From Experimental Design to Differential Expression.Undergraduate Bioinformatics Education Conference (UBEC), St. Vincent’s College, Latrobe PA.
Charles Hauser, Chris Jones, L. Zhou, Wilson Leung, Chris Shaffer, D Lopatto, S CR Elgin (2012) The Genomics Education Partnership (GEP): Comparative Analysis of the Drosophila Dot Chromosome by Undergraduate Students. Undergraduate Bioinformatics Education Conference (UBEC), St. Vincent’s College, Latrobe PA.
Charles Hauser, Wilson Leung, Chris Shaffer, D Lopatto, S CR Elgin (2011) The Genomics Education Partnership. Institutional Research and Academic Career Development Award Conference (IRACDA), Baylor College of Medicine, Houston TX