Chemistry Department Chair
Dr. Toledo has been teaching at St. Ed’s since 2015. He is a Bioinorganic chemist by training and additionally loves to explore questions about how people learn. He maintains and active research group with undergraduate students where they explore how metalloenzymes catalyze incredible molecular transformations. The approach to do this is to synthesize small molecule analogues of these wonderful natural chemical machines.
Dr. Toledo spent six years teaching at Texas Lutheran University where he received tenure before joining the faculty at St. Ed’s. At St. Edward’s. Dr. Toledo has an active research group working on bioniornganic research. Dr. Toledo is also very interested in exploring and developing innovative teaching techniques that can catalyze learning for students in helping them become self-directed, independent learners. He teaches General Chemistry, Organic Chemistry, Inorganic Chemistry II, and Inorganic Chemistry II lab. His favorite course is general chemistry since he enjoys helping students see the beauty of the chemical world.
Associate Professor, Department of Chemistry, St. Edward's University, Aug 2019-Present
Assistant Professor, Department of Chemistry, St. Edward's University, Aug 2015- May 2019
Associate Professor, Department of Chemistry, Texas Lutheran University, Feb 2015-May 2015
Assistant Professor, Department of Chemistry, Texas Lutheran University, 2009-Feb 2015
Spanish and English
Ph.D. Bioinorganic Chemistry, University of Washington, Seattle, WA-2009
B.S Chemistry, Texas Lutheran University, Seguin, TX-2004
Achievement & Involvement
Honors and Awards
2019-2020 School of Natural Sciences Dean's Excellence in Research Award
Organizations, Boards and Memberships
Co-Chair of the Division of Inorganic Chemistry Awards Committee
Principal investigator of a National Institute of Health (NIH)-National Institute of General Medical Sciences (NIGMS) SCORE-2 grant ($330,602). “An expanded family of model complexes for Nickel Acireductone Dioxygenase (Ni-ARD): Towards elucidating the role of metal identity on reactivity and mechanism.”
May 2019-April 2022
Publications & Articles
Blade, G.A. †; Parveen, R.; Jaimes, J.L. †; Ilustre, W. †; Saldaña,D. †; Ivan, D.A. †; Lynch,V.M. Cundari, T.R.; Toledo, S. “A family of structural and functional models for the active site of a unique dioxygenase: Acireductone dioxygenase (ARD)” Journal of Inorganic Biochemistry, 2020.
Healy, E. F.; Flores, R.†; Lynch, V.M.; Toledo, S. “Protein dynamics of [CuZn]superoxide dismutase (SOD1): How protein motions at the global and local levels impact the reactivity of SOD1” Journal of Inorganic Biochemistry, 2020, 210, 111161.
Healy, E.; Roth-Rodriguez, A.; Toledo, S. "A model for gain of function in superoxide dismutase" Biochemistry and Biophysics Reports. 2020, 21, 100728.
Yan Poon, P.C., Dedushko, M.A., Sun, X., Yang, G., Toledo, S., Hayes, E.C., Johansen, A., Piquette, M.C., Rees, J.A., Stoll, S. and Rybak-Akimova, E., 2019. How Metal Ion Lewis Acidity and Steric Properties Influence the Barrier to Dioxygen Binding, Peroxo O–O Bond Cleavage, and Reactivity. Journal of the American Chemical Society, 141(38), pp.15046-15057.
Ivan, D.A*; Gremillion, A.J.*; Sanchez,A.*; Sanchez, S.* ;Lynch, V.A.; Toledo, S.A. “The First Structural Model for the Resting State of the Active Site of Nickel Acireductone Dioxygenase (Ni-ARD).” Inorg. Chem. Comm., 2018, 89C, 37-40.
*Denotes undergraduate student collaborators.
Toledo, S.A.; Dubas, J.M. A Learner-Centered Grading Method Focused on Reaching Proficiency with Course Learning Outcomes. J. Chem. Ed., 2017, DOI: 10.1021/acs.jchemed.6b00651
Toledo, S.A.; Dubas, J.M. Encouraging Higher-Order Thinking in General Chemistry by Scaffolding Student Learning Using Marzano's Taxonomy. J. Chem. Ed., 2016, 93, 64-69.
Toledo, S.A.; Dubas, J.M. Active Reading Documents (ARDs): A Tool to Facilitate Meaningful Learning Through Reading. College Teaching, 2015, 63, 27-33.
Dubas, J.M; Toledo, S.A. Taking Higher Order Thinking Seriously: Using Marzano’s Taxonomy in the Economics Classroom. International Review of Economics Education, 2016, 21, 12-20.
Brines, L.M; Coggins, M.K.; Yan Poon, P.C.; Toledo, S.; Kaminsky, W.; Kirk, M.; Kovacs, J.A. “Water-Soluble Fe(II)-H2O Complex with a Weak O–H Bond Transfers a Hydrogen Atom via an Observable Monomeric Fe(III)-OH” Journal of the American Chemical Society, 2015, 137 (6), 2253–2264.
Coggins, M. K.; Toledo, S.; Kovacs, J. A. “Isolation and Characterization of a Dihydroxo-Bridged Iron(III,III)(μ-OH)2 Diamond Core Derived from Dioxygen” Inorganic Chemistry, 2013, 52, 13325-13331.
Coggins, M. K.; Toledo S.; Shaffer, E.; Kaminsky W.; Shearer.; Kovacs, J.A. “Characterization and Dioxygen Reactivity of a New Series of Coordinatively Unsaturated Thiolate-Ligated Manganese(II) Complexes” Inorganic Chemistry, 2012, 51 (12), 6633–6644.